FAHREN LERNEN KAISERSLAUTERN GRUNDLAGEN ERKLäRT

Fahren lernen Kaiserslautern Grundlagen erklärt

Fahren lernen Kaiserslautern Grundlagen erklärt

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Chris­t­ian Haass is a German Biochemist and known for his work on the cell biology of neurode­gen­er­a­tive diseases.

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Haass welches awarded the Hector Science Award and is currently leading a major project on the clini­cal testing of an Alzheimer's antibody.

Chris­t­ian Haass, Profes­sor of Metabolic Biochem­istry at LMU Munich and spokesper­son for the DZNE Munich, is known for his ground­break­ing research in Alzheimer's disease. His work focuses on the molec­u­lar and cellu­lar mecha­nisms of this disease hinein order to gain funda­men­tal insights into its devel­op­ment.

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  Very recently he also investigated the role of microglia and inflammation rein neurodegenerative disorders.  This work Leuchtdiode to the spectacular finding that microglial phagocytosis may Beryllium impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms.  This work resulted hinein the identification of TREM2 as a CSF marker for microglial activity.  In a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 welches abnormally increased 5 years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.

We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of our research.

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